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L'échec d'une insulinothérapie intensifiée par multi-injections (MI) pose la question de la place de l'insulinothérapie par pompe. OPT2MISE est le premier essai multicentrique, randomisé et contrôlé évaluant l'efficacité de la pompe après échec d'un schéma basal-bolus optimisé.495 patients DT2 ont été inclus dans une phase de titration des doses d'insuline de 8 semaines (dose totale>0,7 et<1,8U/kg/j)...
Continuous subcutaneous insulin infusion (CSII) using an external pump is widely used for the treatment of type 1 diabetes, but has been less evaluated in type 2 diabetes. This review analyzes the open-label as well as randomized controlled studies performed in type 2 diabetic patients. The efficacy of CSII is compared with multiple daily injections (MDI) in terms of glycaemic control, weight variation,...
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