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BackgroundUltrasound‐targeted microbubble destruction (UTMD) has proved to be a promising method for gene delivery. However, the feasibility and efficacy of UTMD‐mediated gene delivery to the heart of large animals remain unclear. The present study was to explore the probability of increasing the transfection of microRNA‐21 (miR‐21) in swine heart by UTMD, and to search for the most suitable transfection...
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