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Cerebral blood flow (CBF) is an important physiological metric of neurovascular health that can be measured non-invasively using Arterial Spin Labeling (ASL) MRI. Labeling efficiency (LE) refers to the percentage of the blood spins recruited for the flow estimation and is a crucial parameter for ASL quantification. Traditionally, a labeling efficiency of 0.85 is assumed based on Bloch simulations...
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