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The perturbation…︁ …︁ of glucose uptake in organisms is an essential barometer in various metabolic diseases. In their Full Paper on page 143 ff. S. B. Park et al. report on a novel fluorescent glucose bioprobe that can translocate into cytoplasm by glucose‐specific transport systems through the competition with D‐glucose. Unlike reported glucose bioprobes, such as NBDGs and 2‐deoxyglucoses, this...
We developed a novel fluorescent glucose bioprobe, GB2‐Cy3, for the real‐time and quantitative monitoring of glucose uptake in living cells. We synthesized a series of fluorescent glucose analogues by adding Cy3 fluorophores to the α‐anomeric position of D‐glucose through various linkers. Systematic and quantitative analysis of these Cy3‐labeled glucose analogues revealed that GB2‐Cy3 was the ideal...
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