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Isradipine could be used for the treatment of high blood pressure or Parkinsonism, yet the study on pharmacokinetics (PK) of isradipine is lacking in the Chinese population. The current study aims to assess the dose proportionality, pharmacokinetics and gender effect of isradipine following oral single and multiple doses in Chinese subjects. A randomized, open‐label, parallel‐group trial was conducted...
Background: Rosuvastatin has been reported to be beneficial in the treatment of dyslipidemia. The C max and AUC 0−t of rosuvastatin were reported to be ~2 to 4 times higher in Chinese subjects compared with white subjects after administration of a single 1-mg/kg dose.Objectives: The aims of this study were to assess the pharmacokinetics and tolerability of multiple doses of rosuvastatin...
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