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Sample preparation is one of the most crucial processes in most biochemical applications. Reagents are repeatedly diluted in an appropriate sequence to get a target solution with a specific concentration value. For flow-based microfluidic biochips (FMFBs), several research works have been proposed for reactant minimization. In this paper, we propose the first sample preparation algorithm for microfluidic...
Sample preparation plays an essential role in most biochemical reactions. Raw reactants are diluted to solutions with desirable concentration values in this process. Since the reactants, like infant’s blood, DNA evidence collected from crime scenes, or costly reagents, are extremely valuable, their usage should be minimized whenever possible. In this paper, we propose a two-phased reactant minimization...
Sample preparation plays an essential role in most biochemical reactions. Raw reactants are diluted to solutions with desirable concentration values in this process. In this paper, a survey of existing techniques addressing sample preparation on digital microfluidic biochips (DMFBs) is given. The fundamentals of DMFBs are introduced first. Next, we explain how dilution operations are performed on...
Sample preparation is an essential step in biochemical reactions. Reactants must be diluted to achieve given target concentrations in sample preparation. Since some reactants like costly reagents and infant's blood are valuable, their usage should be minimized during dilution. In this paper, we propose an optimal reactant minimization algorithm, GORMA, for sample preparation on digital microfluidic...
As fabrication process exploits even deeper submicron technology, global interconnect delay is becoming one of the most critical performance obstacles in system-on-chip (SoC) designs nowadays. Recent years latency-insensitive system (LIS), which enables multicycle communication to tolerate variant interconnect delay without substantially modifying pre-designed IP cores, has been proposed to conquer...
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