Search results for: M. Maggiore

Items from 1 to 20 out of 68 results

article

Making in‐the‐moment learning visible: A framework to identify and compare various ways of learning through continuity and discourse change

Jessica M. Karch, Nicolette M. Maggiore, Jennifer R. Pierre‐Louis, Destiny Strange, more

Science Education > 108 > 5 > 1292 - 1328

Small group interactions and interactions with near‐peer instructors such as learning assistants serve as fertile opportunities for student learning in undergraduate active learning classrooms. To understand what students take away from these interactions, we need to understand how and what they learn during the moment of their interaction. This study builds on practical epistemology analysis to develop...

article

International Analgesia, Sedation, and Delirium Practices: a prospective cohort study

Gary D. Owen, Joanna L. Stollings, Shayan Rakhit, Li Wang, more

Journal of Intensive Care > 2019 > 7 > 1 > 1-7

Background While understanding of critical illness and delirium continue to evolve, the impact on clinical practice is often unknown and delayed. Our purpose was to provide insight into practice changes by characterizing analgesia and sedation usage and occurrence of delirium in different years and international regions. Methods We performed a retrospective analysis of two multicenter, international,...

article

Association between ventilatory settings and development of acute respiratory distress syndrome in mechanically ventilated patients due to brain injury

Eva Tejerina, Paolo Pelosi, Alfonso Muriel, Oscar Peñuelas, more

Journal of Critical Care > 2017 > 38 > C > 341-345

In neurologically critically ill patients with mechanical ventilation (MV), the development of acute respiratory distress syndrome (ARDS) is a major contributor to morbidity and mortality, but the role of ventilatory management has been scarcely evaluated. We evaluate the association of tidal volume, level of PEEP and driving pressure with the development of ARDS in a population of patients with brain...

article

Severe hypercapnia and outcome of mechanically ventilated patients with moderate or severe acute respiratory distress syndrome

Nicolas Nin, Alfonso Muriel, Oscar Peñuelas, Laurent Brochard, more

Intensive Care Medicine > 2017 > 43 > 2 > 200-208

Purpose To analyze the relationship between hypercapnia developing within the first 48 h after the start of mechanical ventilation and outcome in patients with acute respiratory distress syndrome (ARDS). Patients and methods We performed a secondary analysis of three prospective non-interventional cohort studies focusing on ARDS patients from 927 intensive care units (ICUs) in 40 countries. These...

article

Design of the prototype of a beam transport line for handling and selection of low energy laser-driven beams

F. Schillaci, M. Maggiore, G.A.P. Cirrone, G. Cuttone, more

Nuclear Instruments and Methods in Physics Research Section A: Accelerators,... > 2016 > 837 > C > 80-87

A first prototype of transport beam-line for laser-driven ion beams to be used for the handling of particles accelerated by high-power laser interacting with solid targets has been realized at INFN. The goal is the production of a controlled and stable beam in terms of energy and angular spread. The beam-line consists of two elements: an Energy Selection System (ESS), already realized and characterized...

article

Progress in the design and construction of SPES at INFN-LNL

G. Bisoffi, G. Prete, A. Andrighetto, V. Andreev, more

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions... > 2016 > 376 > C > 402-407

INFN-LNL is constructing an ISOL (Isotope Separation On Line) facility delivering neutron rich ion beams at 10AMeV or beyond, making use of the linear accelerator ALPI as the secondary accelerator. The facility includes a direct ISOL target based on UC_x and able to reach 10¹³fissions/s. In parallel, an applied physics facility will be developed, with applications in medicine and neutron production...

article

Status of the SPES-charge breeder (SPES-CB) and its beam line at INFN-LNL

Àlessio Galatá, M. Comunian, L. Bellan, M. Maggiore, more

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions... > 2016 > 376 > C > 329-333

The Selective Production of Exotic Species (SPES) facility is under construction at INFN-LNL: aim of this project is the production, ionization and post-acceleration of radioactive ions to perform forefront research in nuclear physics. Radioactive species will be produced by fissions induced by a proton beam impinging on an UC_x target: the proton beam will be delivered by a room temperature cyclotron...

article

Use of high-flow nasal cannula oxygenation in ICU adults: a narrative review

Laurent Papazian, Amanda Corley, Dean Hess, John F. Fraser, more

Intensive Care Medicine > 2016 > 42 > 9 > 1336-1349

Oxygen therapy can be delivered using low-flow, intermediate-flow (air entrainment mask), or high-flow devices. Low/intermediate-flow oxygen devices have several drawbacks that cause critically ill patients discomfort and translate into suboptimal clinical results. These include limitation of the FiO₂ (due to the high inspiratory flow often observed in patients with respiratory failure), and insufficient...

article

Transport and dosimetric solutions for the ELIMED laser-driven beam line

G.A.P. Cirrone, F. Romano, V. Scuderi, A. Amato, more

Nuclear Inst. and Methods in Physics Research, A > 2015 > 796 > Complete > 99-103

Within 2017, the ELIMED (ELI-Beamlines MEDical applications) transport beam-line and dosimetric systems for laser-generated beams will be installed at the ELI-Beamlines facility in Prague (CZ), inside the ELIMAIA (ELI Multidisciplinary Applications of laser–Ion Acceleration) interaction room. The beam-line will be composed of two sections: one in vacuum, devoted to the collecting, focusing and energy...

article

Chemoprophylactic and therapeutic efficacy of thymol in murine cystic echinococcosis

M. Maggiore, P.E. Pensel, G. Denegri, M.C. Elissondo

Parasitology International > 2015 > 64 > 5 > 435-440

Cystic echinococcosis is a zoonotic disease caused by the larval stage of the cestode Echinococcus granulosus. The drugs commonly used against cystic echinococcosis are benzimidazoles. Unfortunately, 20%–40% of cases do not respond favorably to such chemotherapy. Consequently, the search of new therapeutic alternatives such as the use of traditional medicinal plants has been increased. The aim of...

article

Impact of sedation and analgesia during noninvasive positive pressure ventilation on outcome: a marginal structural model causal analysis

Alfonso Muriel, Oscar Peñuelas, Fernando Frutos-Vivar, Alejandro C. Arroliga, more

Intensive Care Medicine > 2015 > 41 > 9 > 1586-1600

Purpose There are limited data available about the role of sedation and analgesia during noninvasive positive pressure ventilation (NPPV). The objective of study was to estimate the effect of analgesic or sedative drugs on the failure of NPPV. Methods We studied patients who received at least 2 h of NPPV as first-line therapy in a prospective observational study carried out in 322 intensive care...

article

The LILIA (laser induced light ions acceleration) experiment at LNF

S. Agosteo, M.P. Anania, M. Caresana, G.A.P. Cirrone, more

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions... > 2014 > 331 > C > 15-19

Laser-matter interaction at relativistic intensities opens up new research fields in the particle acceleration and related secondary sources, with immediate applications in medical diagnostics, biophysics, material science, inertial confinement fusion, up to laboratory astrophysics. In particular laser-driven ion acceleration is very promising for hadron therapy once the ion energy will attain a few...

article

Development of an energy selector system for laser-driven proton beam applications

V. Scuderi, S. Bijan Jia, M. Carpinelli, G.A.P. Cirrone, more

Nuclear Inst. and Methods in Physics Research, A > 2014 > 740 > Complete > 87-93

Nowadays, laser-driven proton beams generated by the interaction of high power lasers with solid targets represent a fascinating attraction in the field of the new acceleration techniques. These beams can be potentially accelerated up to hundreds of MeV and, therefore, they can represent a promising opportunity for medical applications. Laser-accelerated proton beams typically show high flux (up to...

article

45: The ELIMED (Multidisciplinary and Medical applications at the ELI-Beams) network perspectives for laser driven beam applications

G.A.P. Cirrone, M. Borghesi, M. Carpinelli, G. Cuttone, more

Radiotherapy and Oncology > 2014 > 110 > Supplement 1 > S23

article

Study of a Low-power, Fast-neutron-based ADS

M. Ripani, S. Frambati, L. Mansani, M. Bruzzone, more

Physics Procedia > 2014 > 60 > Complete > 54-60

Within European Partitioning & Transmutation research programs, infrastructures specifically dedicated to the study of funda- mental reactor physics and engineering parameters of future fast-neutron-based reactors are very important, being some of these features not available in present zero-power prototypes. This presentation will illustrate the conceptual design of an ADS with high safety standards,...

article

An intrinsically safe facility for forefront research and training on nuclear technologies — The beam transport system

L. Calabretta, M. Maggiore, M. Schillaci

The European Physical Journal Plus > 2014 > 129 > 4 > 1-5

A transport beam line from the 70 MeV cyclotron to the beryllium target inside the reactor core has been designed using the PSI Graphic TRANSPORT code. The obtained beam spot at the end of the transport line is 1.5cm in radius with an angular divergence of 0.9mrad, in agreement with the target design. The chromatic behavior of the proposed layout, which has been evaluated and resulted in a Δp/p =...

article

An intrinsically safe facility for forefront research and training on nuclear technologies — An example of accelerator: the SPES cyclotron

M. Maggiore, A. Lombardi, L. A. C. Piazza, G. Prete

The European Physical Journal Plus > 2014 > 129 > 4 > 1-6

The SPES project, under construction at INFN, Laboratori Nazionali di Legnaro, is a research facility for nuclear and applied physics, based on a high-current H^- cyclotron with two exits. One exit will be devoted to supply an ISOL facility for the production of radioactive beams, the second one can be used as driver for the ADS system. The main characteristics of the cyclotron are described together...

article

Status report of the Thomson spectrometer for LILIA experiment

M. Maggiore, G.A.P. Cirrone, F. Romano, A. Caruso, more

Applied Surface Science > 2013 > 274 > Complete > 401-404

LILIA is an experiment of light ions acceleration trough laser interaction with thin metal targets to be done at the FLAME facility, which is now running in INFN-LNF of Frascati (Rome). In the framework of LILIA, the LNS is involved in the design and construction of a spectrometer based on the Thomson's configuration in order to diagnostic the ion ejection from the laser-generated plasma. The main...

article

The semi-seated position slightly reduces the effort to breathe during difficult weaning

N. Deye, F. Lellouche, S. M. Maggiore, S. Taillé, more

Intensive Care Medicine > 2013 > 39 > 1 > 85-92

Purpose The influence of posture on breathing effort in patients with difficult weaning is unknown. We hypothesized that posture could modulate the breathing effort in difficult-to-wean patients. Methods A prospective, crossover, physiologic study was performed in 24 intubated patients breathing with pressure support who had already failed a spontaneous breathing trial or an extubation episode....

article

Year in review in Intensive Care Medicine 2012: I. Neurology and neurointensive care, epidemiology and nephrology, biomarkers and inflammation, nutrition, experimentals

Massimo Antonelli, Marc Bonten, Maurizio Cecconi, Jean Chastre, more

Intensive Care Medicine > 2013 > 39 > 2 > 232-246

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INFONA - science communication portal

Search results for: M. Maggiore

Making in‐the‐moment learning visible: A framework to identify and compare various ways of learning through continuity and discourse change

International Analgesia, Sedation, and Delirium Practices: a prospective cohort study

Association between ventilatory settings and development of acute respiratory distress syndrome in mechanically ventilated patients due to brain injury

Severe hypercapnia and outcome of mechanically ventilated patients with moderate or severe acute respiratory distress syndrome

Design of the prototype of a beam transport line for handling and selection of low energy laser-driven beams

Progress in the design and construction of SPES at INFN-LNL

Status of the SPES-charge breeder (SPES-CB) and its beam line at INFN-LNL

Use of high-flow nasal cannula oxygenation in ICU adults: a narrative review

Transport and dosimetric solutions for the ELIMED laser-driven beam line

Chemoprophylactic and therapeutic efficacy of thymol in murine cystic echinococcosis

Impact of sedation and analgesia during noninvasive positive pressure ventilation on outcome: a marginal structural model causal analysis

The LILIA (laser induced light ions acceleration) experiment at LNF

Development of an energy selector system for laser-driven proton beam applications

45: The ELIMED (Multidisciplinary and Medical applications at the ELI-Beams) network perspectives for laser driven beam applications

Study of a Low-power, Fast-neutron-based ADS

An intrinsically safe facility for forefront research and training on nuclear technologies — The beam transport system

An intrinsically safe facility for forefront research and training on nuclear technologies — An example of accelerator: the SPES cyclotron

Status report of the Thomson spectrometer for LILIA experiment

The semi-seated position slightly reduces the effort to breathe during difficult weaning

Year in review in Intensive Care Medicine 2012: I. Neurology and neurointensive care, epidemiology and nephrology, biomarkers and inflammation, nutrition, experimentals

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