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Objective
We previously reported that matrix metalloproteinase‐3(MMP‐3) accelerates wound healing following dental pulp injury. In this study, we tested the hypothesis that induction of MMP‐3 activity by interleukin‐1β would promote proliferation and apoptosis of dental pulp cells.
Materials and Methods
Dental pulp cells were isolated from rat incisors and subjected to interleukin‐1β. Matrix metalloproteinase‐3...
ObjectivesMatrix metalloproteinase (MMP)‐3 expression increases after pulpectomy and accelerates angiogenesis in rat dental pulp by an uncharacterised mechanism. Odontoblasts, a major component of dental pulp, could represent a therapeutic target. We investigated whether MMP‐3 activity is induced by cytokines and/or is associated with cell proliferation and apoptosis in embryonic stem cell‐derived...
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