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SHP-2 is a protein tyrosine phosphatase (PTP) that plays an important role in many cellular functions such as development, growth, and death; thus SHP-2 has been hypothesized to play an important role in various diseases such as diabetes, neurodegeneration, and cancer. The importance of the individual roles of different PTPs is not well understood and this is complicated by the lack of specific inhibitors...
The slingshot-2 (SSH-2) protein plays a significant role in different cell functions such as growth and movement. SSH-2 is a phosphatase protein that belongs to a unique class of enzymes called dual specificity phosphatases (DSP) that target the phosphothreonine and phosphotyrosine residues of mitogen-activated protein (MAP) kinases, which regulate cell growth. Because of this, it is of great interest...
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