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Saliva's role in the oral cavity, such as lubrication, protection of tissues and antimicrobial action is a reflex of its composition, among which are several peptide families like statherin, histatins, proline rich proteins (PRPs) and some members of the cystatin family. These peptides present different evolutionary pathways being in the case of histatin, statherin and PRP families restricted to few...
Thymosin β4 (Tβ4) is a low molecular weight peptide found in several mammalian tissues and is known mainly by its ability to bind cytoskeletal actin, influencing cell migration and differentiation, and promoting tissue repair. Considering the functional role of this peptide, the main goal of this work was to characterize Tβ4 in mammals’ saliva by using evolutionary and proteomic tools. For this, mammalian...
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