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Based on the bioactive screening results, four new pregnane glycosides, namely cynanotophyllosides A–D (1–4) were isolated from the anti-depressant active fraction of cultivated Cynanchum otophyllum, along with thirteen known compounds (5–17). The new compounds were characterized as qingyangshengenin 3-O-β-D-glucopyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-cymaropyranoside...
Six new pregnane glycosides with an acyl at C-12 and a straight sugar chain at C-3, namely otophyllosides H–M (1–6), were isolated from the roots of Cynanchum otophyllum (Asclepiadaceae) collected from Eryuan County in Yunnan province of China. Their structures were characterized to be qingyangshengenin 3-O-β-d-glucopyranosyl-(1→4)-β-d-glucopyranosyl-(1→4)-β-d-cymaropyranosyl-(1→4)-β-d-oleandropyranosyl-(1→4)-β-d-digitoxopyranoside...
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