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Alzheimer's disease (AD) induces large-scale neuro-degeneration which may underlie various cognitive problems, and Mild cognitive impairment (MCI) is assumed as its prodromal phase. Studies routinely use structural MRI and DTI to map neuroanatomical basis separately in AD while ignoring the relationship between different modalities. In this study, we use sparse canonical correlation analysis (SCCA),...
A reliable human brain atlas is critical for brain network analysis at macro-scale. Most studies employed existing anatomical brain atlases or randomly parcellated the whole brain into discrete regions. However, these anatomical atlases had a large variation in region sizes, and the random parcellation procedure was lack of explicit biological significance. In this study, we proposed a new brain parcellation...
In the last few years, many studies in the cognitive and system neuroscience found that a consistent network of brain regions, referred to as the default network, showed high levels of activity when no explicit task was performed. Some scientists believed that the resting state activity might reflect some neural functions that consolidate the past, stabilize brain ensembles and prepare us for the...
In the last few years, many studies in the cognitive and system neuroscience found that a consistent network of brain regions, referred to as the default network, showed high levels of activity when no explicit task was performed. Some scientists believed that the resting state activity might reflect some neural functions that consolidate the past, stabilize brain ensembles, and prepare us for the...
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