Search results for: Hiroshi Inaba

Items from 1 to 20 out of 32 results

article

Genetic analysis of carrier status in female members of Japanese hemophilia families

Keiko Shinozawa, Kagehiro Amano, Takeshi Hagiwara, Masato Bingo, more

Journal of Thrombosis and Haemostasis > 19 > 6 > 1493 - 1505

Background Genetic characteristics and genetic carrier diagnosis in Japanese hemophilia female carriers have not been evaluated. Objectives To provide genetic information on Japanese hemophilia female carriers and demonstrate the advantages of genetic testing in carrier diagnosis. Methods DNA sequencing combined with long polymerase chain reaction for inversion and multiplex ligation‐dependent...

article

Immunological Evaluation of Co‐Assembling a Lipidated Peptide Antigen and Lipophilic Adjuvants: Self‐Adjuvanting Anti‐Breast‐Cancer Vaccine Candidates

Taku Aiga, Yoshiyuki Manabe, Keita Ito, Tsung‐Che Chang, more

Angewandte Chemie > 132 > 40 > 17858 - 17864

Co‐assembling vaccines composed of a lipidated HER2‐derived antigenic CH401 peptide and either a lipophilic adjuvant, Pam₃CSK₄, α‐GalCer, or lipid A 506, were evaluated as breast cancer vaccine candidates. This vaccine design was aimed to inherit both antigen multivalency and antigen‐specific immunostimulation properties, observed in reported self‐adjuvanting vaccine candidates, by using self‐assembly...

article

Immunological Evaluation of Co‐Assembling a Lipidated Peptide Antigen and Lipophilic Adjuvants: Self‐Adjuvanting Anti‐Breast‐Cancer Vaccine Candidates

Taku Aiga, Yoshiyuki Manabe, Keita Ito, Tsung‐Che Chang, more

Angewandte Chemie International Edition > 59 > 40 > 17705 - 17711

article

Molecular Encapsulation Inside Microtubules Based on Tau‐Derived Peptides

Hiroshi Inaba, Takahisa Yamamoto, Arif Md. Rashedul Kabir, Akira Kakugo, more

Chemistry – A European Journal > 24 > 56 > 14958 - 14967

Microtubules are cytoskeletal filaments that serve as attractive scaffolds for developing nanomaterials and nanodevices because of their unique structural properties. The functionalization of the outer surface of microtubules has been established for this purpose. However, no attempts have been made to encapsulate molecules inside microtubules with 15 nm inner diameter. The encapsulation of various...

article

Cover Feature: Molecular Encapsulation Inside Microtubules Based on Tau‐Derived Peptides (Chem. Eur. J. 56/2018)

Hiroshi Inaba, Takahisa Yamamoto, Arif Md. Rashedul Kabir, Akira Kakugo, more

Chemistry – A European Journal > 24 > 56 > 14850 - 14850

A methodology for molecular encapsulation inside hollow microtubules has been developed based on the peptide design. A peptide derived from Tau protein binds to a pocket of tubulin (component of microtubules), which is located at the inner surface of the microtubules. The Tau‐derived peptide can be used to encapsulate exogenous cargos inside microtubules. The cover image shows the peptide—gold nanoparticle...

article

Artificial bio-nanomachines based on protein needles derived from bacteriophage T4

Hiroshi Inaba, Takafumi Ueno

Biophysical Reviews > 2018 > 10 > 2 > 641-658

Bacteriophage T4 is a natural bio-nanomachine which achieves efficient infection of host cells via cooperative motion of specific three-dimensional protein architectures. The relationships between the protein structures and their dynamic functions have recently been clarified. In this review we summarize the design principles for fabrication of nanomachines using the component proteins of bacteriophage...

chapter

Simultaneous triangular-decoupling, disturbance-rejection and stabilization problem for infinite-dimensional systems

Naohisa Otsuka, Hiroshi Inaba, Kazuo Toraichi

Lecture Notes in Control and Information Sciences > Analysis and Optimization of Systems: State and Frequency Domain Approaches for Infinite-Dimensional Systems > 290-301

The simultaneous triangular-decoupling, disturbance-rejection and stabilization problem with state feedback for infinite-dimensional linear systems is studied in the framework of geometric approach. Under certain assumptions, some sufficient conditions for the problem to be solvable are presented. Further, the simultaneous triangular-decoupling and disturbance-rejection problem with incomplete-state...

chapter

Muscle-Driven Motion Simulation Based on Deformable Human Model Constructed from Real Anatomical Slice Data

Hiroshi Inaba, Shin-ya Miyazaki, Jun-ichi Hasegawa

Lecture Notes in Computer Science > Articulated Motion and Deformable Objects > Articulated Motion and Deformable Objects AMDO2002 > 32-42

Recently, much research has been reported on human motion simulation which is applicable to sports medicine, rehabilitation, plastic surgery and so on. Digital human body is a general term for those synthesized models and is expected to analyze and evaluate real human’s behaviors. It enables us to experiment various kinds of cases safely without giving patients any pain. However, for the time being,...

chapter

Luenberger-type observers for perspective linear systems

Rixat Abdursul, Hiroshi Inaba, Bijoy K. Ghosh

2001 European Control Conference (ECC) > 2924 - 2929

2001 European Control Conference (ECC)

Perspective dynamical systems arise in machine vision, in which only perspective observation is available, and the essential problem is to estimate the state and /or unknown parameters for a moving rigid body based on the observed information. This paper proposes and studies a Luenberger-type observer for perspective linear systems. In particular, assuming a given perspective linear system to be Lyapunov...

article

Factor X M402T: a homozygous missense mutation identified as the cause of cross-reacting material-reduced deficiency

Yushi Chikasawa, Keiko Shinozawa, Kagehiro Amano, Kyoichi Ogata, more

International Journal of Hematology > 2014 > 100 > 4 > 345-352

We investigated a mildly hemorrhagic patient with factor X (FX) deficiency to identify the nature of his defect by comprehensive analyses. A 42-year-old Japanese man was admitted to our hospital for uncontrolled gingival hemorrhage. His FX activity based on prothrombin time (PT) and activated partial thromboplastin time (aPTT) and FX antigen were <1, 6.5 and 11 %, respectively. A homozygous M402T...

article

Genotypic and phenotypic features of Japanese patients with mild to moderate hemophilia A

Hiroshi Inaba, Keiko Shinozawa, Ikuo Seita, Manabu Otaki, more

International Journal of Hematology > 2013 > 97 > 6 > 758-764

Hemophilia A is the most common inherited bleeding disorder. To better understand the genotypic and phenotypic features of Japanese patients with mild to moderate hemophilia A, we studied 29 unrelated patients with more than 1 % FVIII activity (FVIII:C). Differences were observed in nine of 21 patients in measured FVIII:C levels between the one-stage clotting and chromogenic assays. We identified...

article

Inorganic Design of Protein Assemblies as Supramolecular Platforms

Nusrat J. M. Sanghamitra, Hiroshi Inaba, Susumu Kitagawa, Takafumi Ueno

Journal of Inorganic and Organometallic Polymers and Materials > 2013 > 23 > 1 > 50-60

In the last decade, there has been great deal of progress in the study of self-assembly processes of protein assemblies as biotemplates to create and construct one-dimensional arrays of nanocrystalline metals and semiconductors. Successful attempts in fabricating the protein-based bioelectronics could serve as a promising alternative to synthetic template based nanomaterials. Another perspective of...

article

An efficient approach for counting the number of spanning trees in circulant and related graphs

Talip Atajan, Xuerong Yong, Hiroshi Inaba

Discrete Mathematics > 2010 > 310 > 6-7 > 1210-1221

The most recent general result for counting the exact number of spanning trees in a directed or an undirected circulant graph is that the numbers satisfy a recurrence relation of size 2s−1 where s is the largest jump [29]. A drawback here is that, when the jump s is large, it is difficult to apply the method to get the number of spanning trees because the degree of the recurrence relation grows exponentially...

article

Fabrication of Discrete Track Media by Cr Ion Implantation

Tatsuya Hinoue, Toshinori Ono, Hiroshi Inaba, Tomohiro Iwane, more

IEEE Transactions on Magnetics > 2010 > 46 > 6 > 1584 - 1586

Discrete track media were successfully fabricated by Cr ion implantation. The saturation magnetization of the CoCrPt-SiO₂ perpendicular recording layer was decreased down to 6% by implanting Cr ions with a dosage of 1 ?? 10¹⁷ ions/cm and an ion energy of 20 keV. A resist mask with a discrete track pattern was prepared by e-beam lithography and the pattern was transferred to the recording layer by...

article

Molecular characterization of 3 factor V mutations, R2174L, V1813M, and a 5-bp deletion, that cause factor V deficiency

Keiko Shinozawa, Kagehiro Amano, Takashi Suzuki, Asashi Tanaka, more

International Journal of Hematology > 2007 > 86 > 5 > 407-413

We identified 3 mutations in the factor V (FV) gene(F5) associated with FV deficiency in 3 unrelated Japanese patients. Patient 1 had severe bleeding symptoms (plasma FV activity, <1%; FV antigen, 9%) and was a compound heterozygote for a novel 5-bp deletion in exon 22 and the V1813M mutation. Patient 2 had moderate bleeding symptoms (plasma FV activity, <1%; FV antigen, 4%) and was homozygous...

chapter

Global Output Tracking for a Class of Nonlinear Systems by output feedback

Keylan Alimhan, Hiroshi Inaba

2006 14th Mediterranean Conference on Control and Automation > 1 - 4

2006 14th Mediterranean Conference on Control and Automation

This paper considers a global asymptotic output tracking problem with a prescribed constant reference signal for a class of single-input and single output-output nonlinear systems. It is shown that under some mild conditions on such a system there is a smooth output feedback achieving global asymptotic output tracking and such a smooth output controller is explicitly constructed by a new design method...

article

Further analysis of the number of spanning trees in circulant graphs

Talip Atajan, Xuerong Yong, Hiroshi Inaba

Discrete Mathematics > 2006 > 306 > 22 > 2817-2827

Let 1⩽s1<s2<⋯<sk⩽⌊n/2⌋ be given integers. An undirected even-valent circulant graph, Cns1,s2,…,sk, has n vertices 0,1,2,…, n-1, and for each si(1⩽i⩽k) and j (0⩽j⩽n-1) there is an edge between j and j+si(modn). Let T(Cns1,s2,…,sk) stand for the number of spanning trees of Cns1,s2,…,sk. For this special class of graphs, a general and most recent result, which is obtained in [Y.P. Zhang, X....

article

Output feedback control for a class of nonlinear systems

Keylan Alimhan, Hiroshi Inaba

International Journal of Automation and Computing > 2006 > 3 > 3 > 215-221

This paper studies the global stabilization problem by an output controller for a family of uncertain nonlinear systems satisfying some relaxed triangular-type conditions and with dynamics which may not be exactly known. Using a feedback domination design method, we explicitly construct a dynamic output compensator which globally stabilizes such an uncertain nonlinear system. The usefulness of our...

article

Nonlinear observers for perspective time-invariant linear systems

Rixat Abdursul, Hiroshi Inaba, Bijoy K. Ghosh

Automatica > 2004 > 40 > 3 > 481-490

Perspective dynamical systems arise in machine vision, in which only perspective observation is available. This paper proposes and studies a Luenberger-type nonlinear observer for perspective time-invariant linear systems. Assuming a given perspective time-invariant linear system to be Lyapunov stable and to satisfy some sort of detectability condition, it is shown that the estimation error converges...

article

Five Novel and four recurrent point mutations in the antithrombin gene causing venous thrombosis

Keiko Nagaizumi, Hiroshi Inaba, Kagehiro Amano, Midori Suzuki, more

International Journal of Hematology > 2003 > 78 > 1 > 79-83

We analyzed the antithrombin (AT) gene in 9 unrelated Japanese patients with thrombotic disease. All 7 exons, the splice junctions, and the 5′-flanking region of the AT gene were amplified by polymerase chain reaction and sequenced directly. Nine different point mutations, all in the heterozygous state, were identified. Five novel (M-32T, M89K, L146H, Q159X, and L409P) and 2 previously reported (R132X...

Publication date

Set your own date range

INFONA - science communication portal

Search results for: Hiroshi Inaba

Genetic analysis of carrier status in female members of Japanese hemophilia families

Immunological Evaluation of Co‐Assembling a Lipidated Peptide Antigen and Lipophilic Adjuvants: Self‐Adjuvanting Anti‐Breast‐Cancer Vaccine Candidates

Immunological Evaluation of Co‐Assembling a Lipidated Peptide Antigen and Lipophilic Adjuvants: Self‐Adjuvanting Anti‐Breast‐Cancer Vaccine Candidates

Molecular Encapsulation Inside Microtubules Based on Tau‐Derived Peptides

Cover Feature: Molecular Encapsulation Inside Microtubules Based on Tau‐Derived Peptides (Chem. Eur. J. 56/2018)

Artificial bio-nanomachines based on protein needles derived from bacteriophage T4

Simultaneous triangular-decoupling, disturbance-rejection and stabilization problem for infinite-dimensional systems

Muscle-Driven Motion Simulation Based on Deformable Human Model Constructed from Real Anatomical Slice Data

Luenberger-type observers for perspective linear systems

Factor X M402T: a homozygous missense mutation identified as the cause of cross-reacting material-reduced deficiency

Genotypic and phenotypic features of Japanese patients with mild to moderate hemophilia A

Inorganic Design of Protein Assemblies as Supramolecular Platforms

An efficient approach for counting the number of spanning trees in circulant and related graphs

Fabrication of Discrete Track Media by Cr Ion Implantation

Molecular characterization of 3 factor V mutations, R2174L, V1813M, and a 5-bp deletion, that cause factor V deficiency

Global Output Tracking for a Class of Nonlinear Systems by output feedback

Further analysis of the number of spanning trees in circulant graphs

Output feedback control for a class of nonlinear systems

Nonlinear observers for perspective time-invariant linear systems

Five Novel and four recurrent point mutations in the antithrombin gene causing venous thrombosis

Filter options

Publication date

Content availability

Publication type

Keywords

Data set

Journal

INFONA - science communication portal

Search results for: Hiroshi Inaba

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Content availability

Publication type

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options