The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
BACKGROUND
A surge of vascular endothelial growth factor (VEGF) after transarterial chemoembolization (TACE) may contribute to tumor progression. Axitinib is a potent antiangiogenic agent with main activity against VEGF receptors 1 to 3. To the authors' knowledge, its role in combination with TACE for the treatment of patients with inoperable hepatocellular carcinoma (HCC) is unclear.
METHODS
A...
BACKGROUNDSingle nucleotide polymorphism (SNP) of the excision repair cross‐complementing group 1 (ERCC1) gene has been linked with sensitivity to platinum and radiation. The authors hypothesized that the ERCC1 genotype for the SNPs cytosine‐to‐thymine substitution at codon 118 (C118T) and cytosine‐to‐adenine substitution at codon 8092 (C8092A) is prognostic in patients with nasopharyngeal carcinoma...
BACKGROUNDThis study evaluated the activity of 2 schedules of erlotinib in combination with chemotherapy, and the prognostic significance of serum amphiregulin (AREG) and transforming growth factor alpha (TGFa) in metastatic colorectal cancer.
METHODSA total of 60 untreated patients were randomized to a “continuous” (CON; erlotinib 100 mg daily) or an “intermittent” (INT; erlotinib 150 mg on alternate...
BACKGROUND:The level of circulating interleukin 10 (IL‐10) is elevated in a proportion of patients with hepatocellular carcinoma (HCC). The objective of the current study was to evaluate the prognostic significance of serum the IL‐10 level in patients with unresectable HCC.
METHODS:Patients with unresectable HCC who provided serum at the time of diagnosis were enrolled prospectively in the study...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.