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A polymeric hindered amine light stabilizer (HALS), wherein the HALS functionality was attached to the terminal chain end of an alternating ethylene-propylene copolymer has been synthesized by terminating the living anionic polymerization of isoprene with 4(2,3-epoxy prppoxy)-1,2,2,6,6-pentamethylpiperidine followed by hydrogenation of the resulting polymer using Ziegler type catalyst. The solubility...
The maximum steady state flux, diffusion coefficients and solubilities of piroxicam, a water insoluble drug and theophylline, a water soluble drug in poly(alkylene carbonate)s of varying alkyl chain lengths were determined and compared with poly(lactide)s. The permeabilities were found to be profoundly affected by the nature of the permeant as well as the polymer properties. Comparative studies...
Brefeldin A (BFA), a unique fungal metabolite of a 13-membered lactone ring, exhibits various biological actions, including antitumor, antifungal and antiviral activities. In the present study, mouse L B cells were treated with various concentrations of interferon (IFN) and/or BFA overnight and infected with encephalomyocarditis virus (EMCV) after removal of IFN and BFA. Doses of BFA which...
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