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We have previously introduced methods for noninvasive estimation of temperature change using diagnostic ultrasound. The basic principle was validated both in vitro and in vivo by several groups worldwide. Some limitations remain, however, that have prevented these methods from being adopted in monitoring and guidance of minimally invasive thermal therapies, e.g., RF ablation and high-intensity-focused...
We have recently developed a robust 2D post-beamforming filter for contrast restoration in ultrasound imaging systems using coarsely-sampled array apertures, e.g. high frequency ultrasound (HFUS). The filter can be derived from a discretized 2D impulse response model in the region of interest (ROI). The key to the robustness of the regularized 2D pseudoinverse filter is transforming the operator to...
We present specialized ultrasound imaging modes for monitoring and guidance of noninvasive and minimally-invasive thermal therapy. One mode is based on two-dimensional imaging of temperature change using diagnostic ultrasound. We have validated this method both in vivo and in vitro in monitoring the heating patterns produced by noninvasive HIFU source and minimally-invasive RF ablation device, respectively...
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