Search results for: G. Wade

Items from 1 to 20 out of 134 results

article

COVID‐19 vaccination strategies in Africa: A scoping review of the use of mathematical models to inform policy

Sylvia K. Ofori, Emmanuelle A. Dankwa, Eve Hiyori Estrada, Xinyi Hua, more

Tropical Medicine & International Health > 29 > 6 > 466 - 476

Objective Mathematical models are vital tools to understand transmission dynamics and assess the impact of interventions to mitigate COVID‐19. However, historically, their use in Africa has been limited. In this scoping review, we assess how mathematical models were used to study COVID‐19 vaccination to potentially inform pandemic planning and response in Africa. Methods We searched six electronic...

article

Resilience of the oral microbiome

William G. Wade

Periodontology 02000 > 86 > 1 > 113 - 122

The human mouth harbors a complex microbiota, the composition of which is potentially influenced by a wide range of factors, including the intake of food and drink, the availability of endogenous nutrients, the host immune system, drug treatments, and systemic diseases. Despite these possible influences, the oral microbiota is remarkably resilient, particularly in comparison with the microbiota of...

article

The Geometry of the roots of the Brachial Plexus

Ryckie G. Wade, Emily R. Bligh, Kieran Nar, Rebecca S. Stone, more

Journal of Anatomy > 237 > 6 > 999 - 1005

Diffusion tensor magnetic resonance imaging (DTI) can be used to reconstruct the brachial plexus in 3D via tracts connecting contiguous diffusion tensors with similar primary eigenvector orientations. When creating DTI tractograms, the turning angle of connecting lines (step angle) must be prescribed by the user; however, the literature is lacking detailed geometry of brachial plexus to inform such...

article

Self‐Construal and Forgiveness Revisited: Replication and Extension

Jennifer L. L. Major, Nathaniel G. Wade, Rachel E. Brenner

Counseling and Values > 65 > 2 > 170 - 188

Evidence suggests that people who have greater interdependent self‐construal forgive others more often because they are motivated to forgive to maintain the relationship. Furthermore, such forgiveness might lead to greater emotional well‐being. In this study, we examined the relationship between interdependent self‐construal and (a) decisional forgiveness and (b) emotional well‐being. We also tested...

article

World Workshop on Oral Medicine VII: Targeting the oral microbiome Part 2: Current knowledge on malignant and potentially malignant oral disorders

Jairo Robledo‐Sierra, Dalit Porat Ben‐Amy, Elena Varoni, Roxanne Bavarian, more

Oral Diseases > 25 > S1 > 28 - 48

Objective The World Workshop on Oral Medicine VII chose the oral microbiome as a focus area. Part 1 presents the methodological state of the science for oral microbiome studies. Part 2 was guided by the question: What is currently known about the microbiome associated with oral squamous cell carcinoma and potentially malignant disorders of the oral mucosa? Materials and Methods A scoping review...

article

World Workshop on Oral Medicine VII: Targeting the microbiome for oral medicine specialists—Part 1. A methodological guide

Elena M. Varoni, Roxanne Bavarian, Jairo Robledo‐Sierra, Dalit Porat Ben‐Amy, more

Oral Diseases > 25 > S1 > 12 - 27

Advances in high‐throughput sequencing technologies have allowed for a rapid increase in knowledge about the human microbiome in both healthy and diseased states, which is expected to increase our understanding of multifactorial diseases. The World Workshop on Oral Medicine VII chose the microbiome as one of its topics of focus. Part 1 of this review provides updated knowledge in the field of microbiome...

article

Systematic review of fibrin glue in burn wound reconstruction

R. Miller, J. C. R. Wormald, R. G. Wade, D. P. Collins

British Journal of Surgery > 106 > 3 > 165 - 173

Background In the reconstruction of burns using split‐skin grafts (SSGs), fibrin glue can be used to improve graft take and reduce haematoma formation, although the efficacy and cost‐effectiveness are unknown. This systematic review evaluated outcomes of fibrin glue compared with conventional SSG attachment techniques. Outcomes of interest included SSG take, haematoma formation, patient satisfaction...

article

ASO Author Reflections: Hematological Biomarkers of Survival in Cutaneous Melanoma

Alyss V. Robinson, Howard Peach, Ryckie G. Wade

Annals of Surgical Oncology > 2018 > 25 > 3 > 910-911

ASO Author Reflections is a brief invited commentary on the article “Baseline Neutrophil–Lymphocyte and Platelet–Lymphocyte Ratios as Biomarkers of Survival in Cutaneous Melanoma: A Multicenter Cohort Study”, Ann Surg Oncol. 2018;25:3341–3349.

article

Baseline Neutrophil–Lymphocyte and Platelet–Lymphocyte Ratios as Biomarkers of Survival in Cutaneous Melanoma: A Multicenter Cohort Study

Ryckie G. Wade, Alyss V. Robinson, Michelle C. I. Lo, Claire Keeble, more

Annals of Surgical Oncology > 2018 > 25 > 11 > 3341-3349

Background In the peripheral blood, the neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) change in response to malignancy. These biomarkers are associated with adverse outcomes in numerous cancers, but the evidence is limited in relation to melanoma. This study sought to investigate the association between these biomarkers and survival in Stages I–III cutaneous melanoma. Methods...

article

Magnetic resonance imaging for detecting root avulsions in traumatic adult brachial plexus injuries: protocol for a systematic review of diagnostic accuracy

Ryckie G. Wade, Yemisi Takwoingi, Justin C. R. Wormald, John P. Ridgway, more

Systematic Reviews > 2018 > 7 > 1 > 1-6

Background Adult brachial plexus injuries (BPI) are becoming more common. The reconstruction and prognosis of pre-ganglionic injuries (root avulsions) are different to other types of BPI injury. Preoperative magnetic resonance imaging (MRI) is being used to identify root avulsions, but the evidence from studies of its diagnostic accuracy are conflicting. Therefore, a systematic review is needed to...

article

Perforator mapping reduces the operative time of DIEP flap breast reconstruction: A systematic review and meta-analysis of preoperative ultrasound, computed tomography and magnetic resonance angiography

Ryckie G. Wade, James Watford, Justin C.R. Wormald, Russell J. Bramhall, more

Journal of Plastic, Reconstructive & Aesthetic Surgery > 2018 > 71 > 4 > 468-477

Prior to DIEP flap breast reconstruction, mapping the perforators of the lower abdominal wall using ultrasound, computed tomography angiography (CTA) or magnetic resonance angiography (MRA) reduces the risk of flap failure. This review aimed to investigate the additional potential benefit of a reduction in operating time.We systematically searched the literature for studies concerning adult women...

article

Correction to: Reply to ‘‘Complications in DIEP Flap Breast Reconstruction After Mastectomy for Breast Cancer: A Prospective Cohort Study Comparing Unilateral Versus Bilateral Reconstructions”

Ryckie G. Wade, Sergio Razzano, Elaine M. Sassoon, Richard M. Haywood, more

Annals of Surgical Oncology > 2017 > 24 > 3 > 683-683

In the original article Justin C. R. Wormald’s middle initials were incorrect. They are correct as reflected in this erratum. The original article has also been corrected.

article

Reply to “Complications in DIEP Flap Breast Reconstruction After Mastectomy for Breast Cancer: A Prospective Cohort Study Comparing Unilateral Versus Bilateral Reconstructions”

Ryckie G. Wade, Sergio Razzano, Elaine M. Sassoon, Richard M. Haywood, more

Annals of Surgical Oncology > 2017 > 24 > 3 > 563-565

article

The Two Faces of Postural Control in Older Adults: Stability and Function

Ruth Rath, Michael G. Wade

EBioMedicine > 2017 > 21 > Complete > 5-6

article

The Microbiome of Infants Recruited to a Randomised Placebo-controlled Probiotic Trial (PiPS Trial)

Michael Millar, Jo Seale, Melanie Greenland, Pollyanna Hardy, more

EBioMedicine > 2017 > 20 > Complete > 255-262

The microbial dysbiosis associated with necrotizing enterocolitis (NEC) in preterm infants suggests that early exposure to probiotics may decrease and antibiotics may increase NEC risk. However, administration of Bifidobacterium breve strain BBG-001 to preterm infants did not affect NEC incidence in a multicenter randomised controlled phase 3 trial (PiPS trial). Using a subset of these subjects we...

article

Application of a nonradioactive assay for high throughput screening for inhibition of thyroid hormone uptake via the transmembrane transporter MCT8

Hongyan Dong, Michael G. Wade

Toxicology in Vitro > 2017 > 40 > C > 234-242

Thyroid hormones (THs) play important roles in almost all physiological processes. High-throughput screening (HTS) assays are needed to screen the vast numbers of chemicals for their potential to disrupt TH signalling. The current work has confirmed the ability of a rapid assay to identify substances inhibiting TH uptake through monocarboxylate transporter (MCT) 8. Perturbation of MCT8 function results...

article

Complications in DIEP Flap Breast Reconstruction After Mastectomy for Breast Cancer: A Prospective Cohort Study Comparing Unilateral Versus Bilateral Reconstructions

Ryckie G. Wade, Sergio Razzano, Elaine M. Sassoon, Richard M. Haywood, more

Annals of Surgical Oncology > 2017 > 24 > 6 > 1465-1474

Background The demand for bilateral breast reconstructions is rising worldwide. In the UK, approximately 30% of breast cancer patients undergoing mastectomy choose autologous tissue breast reconstruction. Although the deep inferior epigastric perforator (DIEP) flap is gaining popularity, bilateral DIEP flap breast reconstruction remains a complex procedure and reliable outcome data are lacking. In...

article

Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment

Reza Farmahin, Andrew Williams, Byron Kuo, Nikolai L. Chepelev, more

Archives of Toxicology > 2017 > 91 > 5 > 2045-2065

There is increasing interest in the use of quantitative transcriptomic data to determine benchmark dose (BMD) and estimate a point of departure (POD) for human health risk assessment. Although studies have shown that transcriptional PODs correlate with those derived from apical endpoint changes, there is no consensus on the process used to derive a transcriptional POD. Specifically, the subsets of...

article

Severity and management of psoriasis within primary care

Alan G. Wade, Gordon M. Crawford, David Young, Joyce Leman, more

BMC Family Practice > 2016 > 17 > 1 > 1-7

Background Scottish Intercollegiate Guidelines Network and National Institute of Health and Care Excellence guidelines stress the importance of assessing patients with psoriasis for psoriatic arthritis, comorbidities associated with severe disease and quality of life (QoL).The purpose of the study was to evaluate the primary care management of psoriasis in relation to disease severity and QoL from...

article

Contralateral breast symmetrisation in unilateral DIEP flap breast reconstruction

Ryckie G. Wade, Francesco Marongiu, Elaine M. Sassoon, Richard M. Haywood, more

Journal of Plastic, Reconstructive & Aesthetic Surgery > 2016 > 69 > 10 > 1363-1373

Women undergoing unilateral deep inferior epigastric artery perforator (DIEP) flap breast reconstruction may be offered a contralateral symmetrisation either at the time of reconstruction (simultaneous/immediate) or at a later stage (delayed). Simultaneous contralateral breast symmetrisation may be more beneficial to patients and healthcare institutions by avoiding staged surgery, although there is...

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INFONA - science communication portal

Search results for: G. Wade

COVID‐19 vaccination strategies in Africa: A scoping review of the use of mathematical models to inform policy

Resilience of the oral microbiome

The Geometry of the roots of the Brachial Plexus

Self‐Construal and Forgiveness Revisited: Replication and Extension

World Workshop on Oral Medicine VII: Targeting the oral microbiome Part 2: Current knowledge on malignant and potentially malignant oral disorders

World Workshop on Oral Medicine VII: Targeting the microbiome for oral medicine specialists—Part 1. A methodological guide

Systematic review of fibrin glue in burn wound reconstruction

ASO Author Reflections: Hematological Biomarkers of Survival in Cutaneous Melanoma

Baseline Neutrophil–Lymphocyte and Platelet–Lymphocyte Ratios as Biomarkers of Survival in Cutaneous Melanoma: A Multicenter Cohort Study

Magnetic resonance imaging for detecting root avulsions in traumatic adult brachial plexus injuries: protocol for a systematic review of diagnostic accuracy

Perforator mapping reduces the operative time of DIEP flap breast reconstruction: A systematic review and meta-analysis of preoperative ultrasound, computed tomography and magnetic resonance angiography

Correction to: Reply to ‘‘Complications in DIEP Flap Breast Reconstruction After Mastectomy for Breast Cancer: A Prospective Cohort Study Comparing Unilateral Versus Bilateral Reconstructions”

Reply to “Complications in DIEP Flap Breast Reconstruction After Mastectomy for Breast Cancer: A Prospective Cohort Study Comparing Unilateral Versus Bilateral Reconstructions”

The Two Faces of Postural Control in Older Adults: Stability and Function

The Microbiome of Infants Recruited to a Randomised Placebo-controlled Probiotic Trial (PiPS Trial)

Application of a nonradioactive assay for high throughput screening for inhibition of thyroid hormone uptake via the transmembrane transporter MCT8

Complications in DIEP Flap Breast Reconstruction After Mastectomy for Breast Cancer: A Prospective Cohort Study Comparing Unilateral Versus Bilateral Reconstructions

Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment

Severity and management of psoriasis within primary care

Contralateral breast symmetrisation in unilateral DIEP flap breast reconstruction

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