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Purpose
Determine the feasibility of 1H‐[13C] MRS in the mouse hypothalamus using a 14.1T magnet.
Methods
We optimized the design of a 1H‐[13C] surface coil to maximize the signal‐to‐noise ratio of 1H‐[13C] MRS in the mouse hypothalamus. With enhanced signal, 13C accumulation in glucose metabolites was measured in a 8.7 µL voxel in the hypothalamus of 5 healthy mice during the continuous administration...
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