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Phospholipase A2 receptor 1 (PLA2R) mediates collagen-dependent migration. The mechanisms by which PLA2R interacts with collagen remain unclear. We produced HEK293 cells expressing full-length wild-type PLA2R or a truncated PLA2R that lacks fibronectin-like type II (FNII) domains or several regions of C-type lectin-like domain (CTLD). We show that the CTLD1–2 as well as the FNII domain of PLA2R are...
Phospholipase A2 receptor 1 (PLA2R) mediates collagen‐dependent migration. The mechanisms by which PLA2R interacts with collagen remain unclear. We produced HEK293 cells expressing full‐length wild‐type PLA2R or a truncated PLA2R that lacks fibronectin‐like type II (FNII) domains or several regions of C‐type lectin‐like domain (CTLD). We show that the CTLD1–2 as well as the FNII domain of PLA2R are...
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