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Previous experiments with the mouse vas deferens have shown that cannabidiol produces surmountable antagonism of cannabinoid CB 1 receptor agonists at concentrations well below those at which it binds to cannabinoid CB 1 receptors and antagonizes α 1 -adrenoceptor agonists insurmountably. It also enhances electrically evoked contractions of this tissue. We have now found that...
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