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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting the neuromuscular system and does not have a known singular cause. Genetic mutations, extracellular factors, non-neuronal support cells, and the immune system have all been shown to play varied roles in clinical and pathological disease progression. The therapeutic plasticity of mesenchymal stem cells (MSCs) may be well matched...
Customer requirements for extended endurance limit forces the cylinder head design to aim at refinement of coolant flow and improvement in structural fatigue strength. Application of CAE methods to cylinder head development reduces the development cycle time. Coolant flow analysis, thermal analysis and thermal stress analysis are applied to predict temperature and strain. A fatigue life prediction...
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