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α1‐Adrenoceptors are involved in physiological functions such as urinary excretion and ejaculation in the lower urinary tract (LUT). Several α1 antagonists are clinically used for the treatment of urinary obstruction in patients with benign prostatic hyperplasia. At present, three classical α1‐adrenoceptor subtypes (α1A, α1B, and α1D) have been identified, among which the α1A and α1D‐adrenoceptor...
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