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You‐Gui‐Wan is a widely used traditional Chinese medicine preparation for the treatment of osteoporosis with kidney‐yang deficiency, and is composed of both yang‐invigorating and kidney‐tonifying herbs, and yin‐nourishing and kidney essence‐replenishing herbs. Considering that the pharmacokinetics of drugs might differ in different pathological conditions, it is necessary to study the pharmacokinetic...
The herb pair Epimedii Folium–Chuanxiong Rhizoma (EF–CR), derived from the classical traditional Chinese medicine ‘Xian Ling Pi San’, has a distinctive compatibility therapeutic profile and is clinically safe and effective. This study aimed to investigate and compare the pharmacokinetic characteristics of nine analytes in osteoarthritis (OA) rat plasma after the oral administration of EF, CR or a...
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