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Apocynum venetum Linn. (Apocynaceae family), also called Luobuma, is a shrub which grows widely in the Xinjiang Autonomous Region of China. Its leaves are used in herbal tea for the treatment of hypertension, anxiety and depression. Animal studies have also shown that Apocynum venetum leaf extract (AVLE) also exerts anti-depressant and anti-anxiety activities. The effects of AVLE on neuronal tissues...
We examined the effects of peroxynitrite pre-treatment on sarco/endoplasmic reticulum Ca 2+ (SERCA) pump in pig coronary artery smooth muscle and endothelium. In saponin-permeabilized cells, smooth muscle showed much greater rates of the SERCA Ca 2+ pump-dependent 45 Ca 2+ uptake/mg protein than did the endothelial cells. Peroxynitrite treatment...
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