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Surfactants employed in production of solid lipid nanoparticles (SLNs) play a major role on physical stability of nanoparticles, and the extent of drug dissolution and permeability into cells. In this study, cationic (cetyl pyridinium chloride), anionic (sodium dodecyl sulfate) and non-ionic (Tween 80) surfactants, as well as its combinations, were employed to formulate compritol based SLNs using...
Mucoadhesive poly (lactic-co-glycolic acid) (PLGA) nanoparticles having a modified shell-matrix derived from polyvinyl alcohol (PVA) and Carbopol (CP), a biodegradable polymer coating, to improve the adhesion and cell transfection properties were developed. The optimum formulations utilized a CP concentration in the range of 0.05–0.2%w/v, and were formed using modified emulsion-solvent evaporation...
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