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Using a positron autoradiography technique, dynamic changes in the cerebral glucose metabolic rate (CMRglc) induced by hypoxia/reoxygenation were investigated in living brain slices. After incubating fresh rat brain slices (300 μm thick) with [18F]2-fluoro-2-deoxy-d-glucose ([18F]FDG) in oxygenated Krebs–Ringer solution at 36°C, serial two-dimensional time-resolved images of [18F]FDG uptake in the...
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