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BackgroundVolume reduction and RBC depletion of equine bone marrow specimens are necessary processing steps for the immediate therapeutic use of bone marrow (BM)‐derived mesenchymal stem cells (MSC), and for MSC expansion in culture.
ObjectivesThe purpose of the study was to evaluate the ability of the PrepaCyte‐CB processing system to reduce volume, deplete RBC, and recover mononuclear cells (MNC)...
Reasons for performing studyJoint inflammation and septic arthritis are both potential complications of intra‐articular injections of bone marrow‐derived mesenchymal stem cells (BM‐MSCs). Clinicians may prophylactically co‐inject BM‐MSCs admixed with either antimicrobials or hyaluronic acid; however, the effect of these agents on cultured BM‐MSCs is unknown.
ObjectiveTo determine the effects of therapeutic...
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