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Abstract: A novel variation of the estrogen receptor- (ER) gene was identified by polymerase chain reactionsingle-strand conformational polymorphism (PCR-SSCP). It is one base substitution in codon 325 (CCC [allele M] to CCG [allele m]) in exon 4 of the human ER gene. This substitution did not cause an amino acid change. We categorized 306 unrelated Japanese postmenopausal women into three genotypes:...
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