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The aim of this study was to develop a functional nanoparticulate carrier with an enhanced transfection in asialoglycoprotein receptor overexpressed HepG2 cells. A series of chemical modifications of chitosan were conducted by grafting a hydrophilic methoxy poly(ethylene glycol) (MPEG) and a receptor ligand, lactobionic acid (LA). The pegylation efficiency of deacetylated-depolymerized-chitosan (DADP-CS)...
By analyses using high-performance liquid chromatography (HPLC), the polysaccharide extracts from Se-enriched Ganoderma lucidum (Se-GLP) was comprised mainly of glucose, xylose, arabose and mannose in the molar ratio of 1:4.3:0.7:0.18. the infrared (IR) spectra of the Se-GLP displayed a broad stretching intense characteristic peak at around 3402 and 3105cm −1 for the hydroxyl group, and one...
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