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We investigated the effectiveness of ligustrazine (tetramethylpyrazine, TMP) in alleviating pulmonary damage induced by lipopolysaccharide (LPS). Twenty-four healthy male Sprague-Dawley rats were randomly divided into three groups: the blank group, LPS group, and TMP treatment group (TMP group). The LPS group was intraperitoneally injected with LPS (20mg/kg), and the TMP group was intraperitoneally...
Organ protection is a routine therapy in severe burn/scald injuries, and damage mechanisms following early scald injury was not been fully elucidated. Our aim was to verify the beneficial effects of Ligustrazine on pulmonary damage associated with scald injury.Lewis rats were subjected to 30% total body surface area (TBSA) scald injury, and were randomly divided into a burn control (S group) and an...
Organ protection is a routine therapeutic application to severe burn/scald injuries, and organic damage following early scald injury is not absolutely elucidated. Our aim is to verify the good effects of Ligustrazine on pancreatic and renal damage associated with early scald injury.A total of 120 Lewis rats subjected to 30% total body surface area (TBSA) scald injury, were randomly divided into simple...
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