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While active smoking is known to enhance platelet thromboxane production, no data on passive smoking is available yet. The influence of single and repeated exposure to passive smoke for 60 minutes in a 18 m 3 room was assessed in non-smokers as compared to sex and age matched smokers. All the evaluated measures (malondialdehyde, plasma thromboxane B 2 , 11-dehydro-thromboxane B ...
PGI 2 - and TXA 2 -synthesis from vascular tissue samples derived from cultured (endothelial and smooth muscle) cells, rabbit aorta and human bypass surgery were determined using specific radioimmunoassays for the stable derivatives (6-oxo-PGF 1a and TXB 2 , respectively) of these compounds. Cultured cells were incubated in presence of isradipine, rabbits were...
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