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The detection of microsatellite-unstable (microsatellite instability [MSI]) colorectal carcinomas (CRCs) has prognostic value and can help screen for Lynch syndrome. We determined which histologic features are associated with MSI status and presence of germline mutation and/or methylation of MLH1 promoter. Patients diagnosed with CRC were offered participation in the Columbus-area hereditary nonpolyposis...
This study sought to determine the differences in presentation and treatment of young women (≤40 years of age) with breast cancer. A prospective database was analyzed for differences in presentation and care in breast cancer patients ≤40 and >40 years of age. The study group consisted of 1685 women. Younger women were more likely to present with a palpable mass, have estrogen receptor/progesterone...
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