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Background: We discovered that inhibition of transplant arteriosclerosis by estradiol-17β (E2) is associated with both down-regulation of MHC class II antigen expression and inhibition of macrophage infiltration. These inhibitory effects may require estrogen receptor activation in the allograft vessel, we treated the recipients with daily injection of estradiol α and β receptor antagonist ZM-182780...
Background: Several studies have reported that antiplatelet therapy decrease stent thrombosis after elective stent implantation. If coagulation activity dose not act as the main factor for acute stent thrombosis, heparin will have no influence on the thrombosis.Methods: All patients were pre-treated with ticlopidine 200 mg and aspirin 160 mg more than 2 days before the elective stent implantation...
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