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To clarify the effects of dihydrotestosterone (DHT)–induced polycystic ovary syndrome (PCOS) on the insulin-dependent vasodilatation of the thoracic aorta and the role of vitamin D in a rat model.Controlled experimental animal study.Laboratory.Thirty adolescent female Wistar rats.The PCOS model was induced by 10 weeks of DHT treatment (83 μg/d). One-half of the DHT-treated animals also received vitamin...
To investigate the vascular dysfunction caused by insulin resistance in polycystic ovary syndrome (PCOS) and the effectiveness of vitamin D in an animal model.Controlled experimental animal study.Animal laboratory at a university research institute.Thirty female Wistar rats.Rats were divided into groups at age 21–28 weeks. Twenty of them were subjected to dihydrotestosterone (DHT) treatment (83 μg/d);...
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