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The intensive use of diclofenac (DCF), a nonsteroidal anti-inflammatory drug, has led to its wide occurrence in the environment. The present study investigated the potential use of the fungal Scytalidium thermophilum laccase for DCF removal and detoxification. Firstly, the culture conditions for the maximum fungal laccase production were optimized with a hybrid design and the obtained conditions were:...
This work is directed towards Bacillus amyloliquefaciens strain BLB371 metabolite production for biocontrol of fungal phytopathogens. In order to maximise antifungal metabolite production by this strain, two approaches were combined: random mutagenesis and medium component optimization. After three rounds of mutagenesis, a hyper active mutant, named M3-7, was obtained. It produces 7 fold more antifungal...
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