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AbstractObjective: To determine whether inhalation of nitric oxide (INO) can increase the frequency of reversal of acute lung injury (ALI) in nitric oxide (NO) responders. Design: Prospective, open, randomised, multicentre, parallel group phase III trial. Setting: General ICUs in 43 university and regional hospitals in Europe. Patients: Two hundred and sixty-eight adult patients with early ALI. Interventions:...
AbstractObjective: To evaluate the dose response of inhaled nitric oxide (NO) on gas exchange and central haemodynamics in patients with early acute lung injury (ALI). Design: Prospective, multicentre clinical study. Setting: General ICUs in university and regional hospitals. Patients: 18 patients with early ALI according to specified criteria. Interventions: During controlled ventilation an inhalation...
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