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Acute and 90-day subchronic oral toxicity studies of Silk peptide E5K6 were performed in Sprague–Dawley rats. In the acute toxicity study, Silk peptide E5K6 was administered orally to male and female rats at a single dose of 2000 and 5000mg/kg. Mortality, clinical signs and body weight changes were monitored for 14days. There were no treatment-related changes in these parameters. Therefore, the Approximate...
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