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Protein kinase R (PKR), the double-stranded RNA-activated protein kinase, exists in mammalian and fish. PKZ, a PKR-like protein kinase containing Z-DNA binding domains, just exists in fish. PKR and PKZ work synergistically in the antiviral defense by inhibiting intracellular protein translation. The transcriptional factor IRF3 (interferon regulatory factor 3) acts as a key regulator of type I IFN...
There is a lower basal expression of Connexin43 (Cx43) in human gastric cancer BGC-823 cells. In the present study, BGC-823 cells were transfected with recombinant Cx43 adenovirus plasmid vector, and we explored the influences of Cx43 expression on cell proliferation, chemo-sensitivity, colony forming ability, invasion ability and apoptosis. Moreover, we also determined the expression of Pgp, Cx43,...
A variety of studies have evaluated the association between the −786T>C polymorphism in the promoter region of endothelial nitric oxide synthase (eNOS) and risk of coronary artery disease (CAD). However, the results remain conflicting. To better understand the role of eNOS −786T>C polymorphism in CAD risk, we conducted a comprehensive systematic review and meta-analysis.Case–control, cohort...
•A full-length cDNA library from Siberian tiger fibroblasts has been constructed.•ESTs were deposited in the GenBank from KF896402 to KF896586KF896402KF896403KF896404KF896405KF896406KF896407KF896408KF896409KF896410KF896411KF896412KF896413KF896414KF896415KF896416KF896417KF896418KF896419KF896420KF896421KF896422KF896423KF896424KF896425KF896426KF896427KF896428KF896429KF896430KF896431KF896432KF896433KF896434KF896435KF896436KF896437KF896438KF896439KF896440KF896441KF896442KF896443KF896444KF896445KF896446KF896447KF896448KF896449KF896450KF896451KF896452KF896453KF896454KF896455KF896456KF896457KF896458KF896459KF896460KF896461KF896462KF896463KF896464KF896465KF896466KF896467KF896468KF896469KF896470KF896471KF896472KF896473KF896474KF896475KF896476KF896477KF896478KF896479KF896480KF896481KF896482KF896483KF896484KF896485KF896486KF896487KF896488KF896489KF896490KF896491KF896492KF896493KF896494KF896495KF896496KF896497KF896498KF896499KF896500KF896501KF896502KF896503KF896504KF896505KF896506KF896507KF896508KF896509KF896510KF896511KF896512KF896513KF896514KF896515KF896516KF896517KF896518KF896519KF896520KF896521KF896522KF896523KF896524KF896525KF896526KF896527KF896528KF896529KF896530KF896531KF896532KF896533KF896534KF896535KF896536KF896537KF896538KF896539KF896540KF896541KF896542KF896543KF896544KF896545KF896546KF896547KF896548KF896549KF896550KF896551KF896552KF896553KF896554KF896555KF896556KF896557KF896558KF896559KF896560KF896561KF896562KF896563KF896564KF896565KF896566KF896567KF896568KF896569KF896570KF896571KF896572KF896573KF896574KF896575KF896576KF896577KF896578KF896579KF896580KF896581KF896582KF896583KF896584KF896585KF896586...
The FKBP protein family has prolyl isomerase activity and is related in function to cyclophilins. FKBPs are known to be involved in many biological processes including hormone signaling, plant growth, and stress responses through a chaperone or an isomerization of proline residues during protein folding. The availability of complete peach genome sequences allowed the identification of 21 FKBP genes...
The FK506 binding proteins (FKBPs) are abundant and ubiquitous proteins belonging to the large peptidyl-prolylcis-trans isomerase superfamily. FKBPs are known to be involved in many biological processes including hormone signaling, plant growth, and stress responses through a chaperone or an isomerization of proline residues during protein folding. The availability of complete strawberry genome sequences...
Shigella strains are important human pathogens and are normally identified by their O antigens. O antigen is an essential part of the lipopolysaccharide present in the outer membrane of Gram-negative bacteria and plays a role in pathogenicity. Structural and genetic organization of the Shigella boydii type 18 O antigen was investigated. As judged by sugar and methylation analyses and NMR spectroscopy...
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