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Tumor Therapy
In article number 2110094, Jianxun Ding and co‐workers develop a versatile polymer, 1,2‐distearoyl‐sn‐glycero‐3‐phosphoethanolamine‐N‐poly(ethylene glycol)‐alendronate (DPA), for osteosarcoma blockade therapy. DPA not only initiates biomineralization in the peripheral tissue of tumors after insertion into the cytomembrane, but also alleviates bone destruction efficiently, both of which...
Tumor blockade therapy is a promising penetration‐independent antitumor modality, which effectively inhibits the exchange of nutrients, oxygen, and information between the tumor and surrounding microenvironments. However, the current blockade therapy strategies have limited antitumor efficacy due to defects of inadequate tumor obstruction, possible side effects, and short duration. For these reasons,...
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