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Antiangiogenic cancer therapy can be achieved through the targeted delivery of antiangiogenic agents to the endothelial cells of tumor neovasculature. In the present study, we developed a drug delivery system (DDS), nanoparticles conjugated with K237-(HTMYYHHYQHHL) peptides for tumor neovasculature targeting drug delivery. Paclitaxel, a chemotherapeutic agent with potent antiangiogenic activity, was...
Previous study has demonstrated that brushite (CaHPO 4 ·2H 2 O), modified by partial potassium substitution for calcium, can transform quickly into hydroxyapatite (HA, Ca 5 (PO 4 ) 3 OH) when exposed to aqueous salt solutions at room temperature. Analyses techniques used in those studies required sample retrieval from solution, which may alter the sample surface...
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