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Objectives
The objectives of this study were to explore the role and related mechanism of berberine in repairing bone destruction in apical periodontics (AP).
Materials and Methods
AP was established in 14 of 21 male Wistar rats (four weeks of age; 70–80 g) for 3 weeks. The canals were cleaned and administered berberine (2 mg/ml; n = 7) or calcium hydroxide (100 mg/ml; control; n = 7), followed...
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