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Objectives: cGMP has been shown to exert both stimulatory and inhibitory effects on cardiac L-type calcium current (I Ca ). The physiological role of cGMP in regulation of cardiac activity is still controversial. cGMP may be of importance in regulation of I Ca in atrial cells. The present study was focused on the role of cGMP in the modulation of I Ca in rabbit...
Objective: Cyclic GMP has been shown to be in some respects an inhibitory modulator of heart function. Various studies on the modulation of cardiac L-type calcium current (I Ca ) by cGMP in different species show inconsistency and the role of cGMP remains unclear and controversial. The present study was focused on the differences in the modulation of basal I Ca by cGMP...
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