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To explore the effects of adiponectin on the bone metabolism in vivo. Bone mineral density (BMD), bone microstructure, serum adiponectin levels, and biochemical markers of the bone turnover were measured in 12-week-old male Adipo−/− and WT mice. In addition, the osteoclast formation, osteoprotegerin (OPG), and the receptor activator of nuclear factor-κB ligand (RANKL) expression were examined. The...
The purpose of this work is to investigate the age-related changes in body composition and their relationship with bone mineral density decreasing rates (BDR) in central south Chinese postmenopausal women. BDR is the percentage of bone mineral density (BMD) decreasing value relative to the peak bone mass. A cross-sectional study was conducted on 779 healthy postmenopausal women, aged 50–77. Lumbar...
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