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Automated nucleus/cell detection is usually considered as the basis and a critical prerequisite step of computer assisted pathology and microscopy image analysis. However, due to the enormous variability (cell types, stains and different microscopes) and data complexity (cell overlapping, inhomogeneous intensities, background clutters and image artifacts), robust and accurate nucleus/cell detection...
Laser guidance technique employs the optical forces generated from a focused Gaussian laser beam incident on a biological cell to trap and guide the cell along the laser propagation direction. The optical force, which determines the guidance speed, is dependent on the cellular characteristics of the cell being guided, such as size, shape, composition and morphology. Different cell populations or subpopulations...
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