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The use of nonsteroidal anti-inflammatory drugs (NSAIDs) is ubiquitous in contemporary medical practice and these agents are efficacious in a number of clinical contexts. In particular, NSAIDs have proven to be highly effective adjuncts in the amelioration of postoperative pain in the subset of patients undergoing spinal surgery requiring fusion. NSAIDs act through inhibition of cyclooxygenase enzymes...
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