The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Objective
MicroRNA (miRNA) processing genes play important roles in the craniofacial development. The aim of this study was to explore the associations between single nucleotide polymorphisms (SNPs) of miRNA processing genes with the risk of non‐syndromic orofacial clefts (NSOC).
Methods
We genotyped 12 potentially functional SNPs from seven miRNA processing genes (GEMIN3, DROSHA, DGCR8, GEMIN4...
Objective
Previous genomewide association studies (GWAS) identified a region near MAFB at chr20q12 associated with non‐syndromic orofacial clefts (NSOC) susceptibility. However, whether other SNPs in this area could independently contribute to non‐syndromic orofacial clefts in Chinese populations remained obscure.
Materials and Methods
We selected 24 SNPs based on a haplotype‐tagging SNP strategy...
ObjectiveFOXE1 plays an important role in craniofacial development. The aim of this study was to investigate associations between genetic variants of FOXE1 and risk of non‐syndromic orofacial clefts in a Chinese population.
Materials and MethodsThree potentially functional SNPs of FOXE1 (rs3758250 and rs907577 in the 5′ upstream and rs7043516 in the 3′‐UTR) were selected and their associations with...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.