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Aim
CCN family member 1 (CCN1) is an extracellular matrix cytokine and appears in atherosclerotic lesions. However, we have no evidence to support the role of CCN1 in regulating cholesterol metabolism and atherosclerosis.
Methods
Apolipoprotein E‐deficient (apoE−/−) mice were used as in vivo model. Oxidized low‐density lipoprotein (oxLDL)‐induced macrophage‐foam cells were used as in vitro model...
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