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Influenza can trigger heart attacks, and vaccination against influenza reduces the risk of cardiovascular events. Currently, it is believed that influenza virus in general does not disseminate to extra-pulmonary tissues. We assessed the vascular effects of influenza infection and whether the virus can directly infect atherosclerotic arteries in mice.We intranasally infected 4 different types of mice—atherosclerotic...
Influenza is a major cause of morbidity and mortality. Influenza epidemics lead to an increase in pneumonia-influenza deaths and a considerable increase in death due to cardiovascular disease (CVD). The effects of influenza infection on CVD are just being recognized. Many cases of myocardial infarctions (MI) are preceded by an upper respiratory infection. Influenza vaccination has been associated...
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