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1. Changes in behavioral dopaminergic and serotonergic sensitivities were studied in rats after withdrawal of the chronic treatments with SM-9018 (0.1 mg/kg/day), a potential atypical neuroleptic, and with haloperidol (0.3 mg/kg/day) using continuous infusion pumps.2. Administration of SM-9018 inhibited the rat locomotor activities to an extent similar to that of haloperidol during the course of the...
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