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We have previously shown that dilatation of the uterine cervix at term parturition involves degradation of type I collagen by interstitial collagenase. Tissue plasminogen activator (TPA) and urokinase plasminogen activator (UPA) catalyze the conversion of plasminogen to plasmin which activates latent collagenase. The aim of this study is to investigate the role of the plasminogen activation system...
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